What
is Bextra?
Bextra is part of a class
of drugs call Non-steroidal anti-inflammatory drugs or NSAIDs. The active
ingredient in Bextra is valdecoxib and works as a cyclooxygenase (COX)-2
specific inhibitor.
What
medical conditions is Bextra used to treat?
Bextra is used for relief
from the signs and symptoms of rheumatoid arthritis, osteoarthritis, and
primary dysmenorrhea (painful menstruation).
What is
a Typical Bextra Dosage
The typical Bextra
dosages are 10mg and 20 mg
Who
should not take Bextra?
You should not take Bextra if you:
- had asthma, hives or allergic
reactions after taking aspirin or other NSAIDs (nonsteroidal
anti-inflammatory drugs) or COX-2 inhibitors. Some examples of NSAIDs are
ibuprofen (Motrin, Advil), naproxen (Naprosyn, Aleve), diclofenac (Voltaren,
Cataflam), nabumetone (Relafen), ketoprofen (Orudis), celecoxib (Celebrex),
and rofecoxib (Vioxx). You can ask your doctor or pharmacist for a
complete list of these medications
- are allergic to valdecoxib (Bextra)
or to any of the ingredients in Bextra
Special
Warnings with Bextra
Bextra and all NSAID medications can
cause stomach ulcers that bleed. The chance of this serious problem
increases the longer you take Bextra, but it can also happen suddenly. Stop
taking Bextra and call your doctor right away if you get:
- a burning stomach pain
- black bowel movements that look like
tar
- vomit that looks like blood or
coffee ground
General Precautions
with Bextra
Bextra and other NSAID medications can
cause serious problems such as liver damage. Some of the warning signs of
liver damage are nausea, vomiting, tiredness, loss of appetite, itching,
yellow coloring of skin or eyes, “flu-like” symptoms and dark urine. If this
happens, stop taking Bextra and call your doctor right away.
- Bextra can cause fluid retention
(holding of water in your body). Fluid retention can be a serious problem
if you have high blood pressure or heart failure.
Do not use Bextra if you have asthma
and are allergic to aspirin. If an aspirin-sensitive asthmatic takes aspirin
it can cause severe narrowing of the airway (bronchospasm), and even death.
The same reactions to aspirin and other NSAID medicines happened in
aspirin-sensitive patients.
What should I tell
my health care provider when considering Bextra?
Tell your health care provider if you:
- have heart problems or high blood
pressure
- have liver or kidney problems
- have or had stomach ulcers or stomach
bleeding
- have asthma
- are allergic to aspirin or other NSAID
medicines
- are pregnant or planning to become
pregnant
- are breast-feeding
Tell your health care provider about all
the medicines that you are taking, including prescription and
non-prescription medicines, vitamins, and herbal supplements. Your health
care provider may have to adjust your dose or watch you more closely if you
take the following medications:
- certain blood pressure medicines
called ACE inhibitors
- furosemide (Lasix)
- fluconazole or ketoconazole
- lithium
- warfarin (coumadin)
- aspirin
What are
Bextra's Side effects
- Indigestion
- Nausea
- Stomach pain
- Upper respiratory tract infection
- Diarrhea
- Headache
Rarely serious ulcers and stomach
bleeding have occurred in patients taking Bextra.
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