The Bextra (valdecoxib) Report
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"What You Absolutely Must Know About Bextra & Pain Relievers To Avoid The Same Mistakes That Put 70,000,000* People In Peril"
*National Council on Patient Information and Education NCPIE - Interactive Survey, January 2002

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When I read that statistic my jaw dropped. Every year millions of people turn to OTC and Rx pain relievers like Celebrex and other NSAIDs for help. Every year millions unknowingly put their near and long term health at risk.

Why? Because they just want the pain to stop.

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Each year over 100,000 people end up in the hospital and over 16,000 people die as the result from complications using aspirin, Celebrex and other common NSAIDs.  Source: Singh, Gurkirpal and Rosen Ramy, Dena. NSAID induced Gastrointestinal Complications: the ARAMIS Perspective 1997.

What is Bextra?

Bextra is part of a class of drugs call Non-steroidal anti-inflammatory drugs or NSAIDs. The active ingredient in Bextra is valdecoxib and works as a cyclooxygenase (COX)-2 specific inhibitor.

What medical conditions is Bextra used to treat?

Bextra is used for relief from the signs and symptoms of rheumatoid arthritis, osteoarthritis, and primary dysmenorrhea (painful menstruation).

What is a Typical Bextra Dosage

The typical Bextra dosages are 10mg and 20 mg

Who should not take Bextra? 

You should not take Bextra if you: 

  • had asthma, hives or allergic reactions after taking aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs) or COX-2 inhibitors. Some examples of NSAIDs are ibuprofen (Motrin, Advil), naproxen (Naprosyn, Aleve), diclofenac (Voltaren, Cataflam), nabumetone (Relafen), ketoprofen (Orudis), celecoxib (Celebrex), and rofecoxib (Vioxx). You can ask your doctor or pharmacist for a complete list of these medications 
  • are allergic to valdecoxib (Bextra) or to any of the ingredients in Bextra

Special Warnings with Bextra

Bextra and all NSAID medications can cause stomach ulcers that bleed. The chance of this serious problem increases the longer you take Bextra, but it can also happen suddenly. Stop taking Bextra and call your doctor right away if you get: 

  • a burning stomach pain 
  • black bowel movements that look like tar 
  • vomit that looks like blood or coffee ground

General Precautions with Bextra

Bextra and other NSAID medications can cause serious problems such as liver damage. Some of the warning signs of liver damage are nausea, vomiting, tiredness, loss of appetite, itching, yellow coloring of skin or eyes, “flu-like” symptoms and dark urine. If this happens, stop taking Bextra and call your doctor right away. 

  • Bextra can cause fluid retention (holding of water in your body). Fluid retention can be a serious problem if you have high blood pressure or heart failure. 

Do not use Bextra if you have asthma and are allergic to aspirin. If an aspirin-sensitive asthmatic takes aspirin it can cause severe narrowing of the airway (bronchospasm), and even death. The same reactions to aspirin and other NSAID medicines happened in aspirin-sensitive patients. 

What should I tell my health care provider when considering Bextra?

Tell your health care provider if you: 

  • have heart problems or high blood pressure 
  • have liver or kidney problems 
  • have or had stomach ulcers or stomach bleeding 
  • have asthma 
  • are allergic to aspirin or other NSAID medicines 
  • are pregnant or planning to become pregnant 
  • are breast-feeding 

Tell your health care provider about all the medicines that you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements. Your health care provider may have to adjust your dose or watch you more closely if you take the following medications: 

  • certain blood pressure medicines called ACE inhibitors 
  • furosemide (Lasix) 
  • fluconazole or ketoconazole 
  • lithium 
  • warfarin (coumadin) 
  • aspirin 

What are Bextra's Side effects 

  • Indigestion 
  • Nausea 
  • Stomach pain 
  • Upper respiratory tract infection 
  • Diarrhea 
  • Headache 

Rarely serious ulcers and stomach bleeding have occurred in patients taking Bextra.

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